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Level 1 of 6Core

Bradyarrhythmias and heart block

The core to-do list — diagnose and manage, at a glance

Diagnose— recognise it

  • Define it: ventricular rate below 60/min — but 50/min or lower is normal in healthy people and athletes may rest below 40/min; what makes it a disease is haemodynamic compromise or the level of block.
  • Any one adverse feature = bradycardia with compromise: systolic BP < 90 mmHg with pallor, sweating, cold peripheries or confusion; syncope; ischaemic chest pain or new ST shift; heart failure; rate < 40/min; or any pause > 3 seconds.
  • Measure the escape QRS width on ECG — the cardinal measurement: narrow (< 0.12 s) = block at/above AV node, escape 50–60/min, often atropine-responsive; broad (> 0.12 s) = escape below the His bundle at 15–40/min, unreliable, prone to Stokes–Adams attacks, usually atropine-unresponsive.
  • Dangerous even without symptoms: Mobitz type II (dropped QRS with constant PR, QRS usually wide), third-degree block (complete AV dissociation, escape usually < 50/min), ventricular standstill, bifascicular block with syncope, long QT with bradycardia, and any bradycardia with anterior myocardial infarction.
  • Exclude the mimics at the bedside: hyperkalaemia (tall tented T waves, broad QRS, absent P); the Cushing response — bradycardia with *hypertension* and falling conscious level is raised intracranial pressure; hypothermia; digoxin toxicity (a *regular* slow rhythm in known atrial fibrillation); and monitor artefact.
  • Children — bradycardia is hypoxia until proved otherwise: neonate < 100/min abnormal, < 60/min peri-arrest; infant or child < 60/min with poor perfusion (reduced consciousness, mottling, capillary refill > 2 s, weak central pulses) is peri-arrest.

Manage now— do this, in order

  • Lie flat, raise the legs, give oxygen and correct hypoxaemia — in children this may be the entire treatment; attach continuous ECG monitoring with a defibrillator and pacing pads at the bedside.Not available at your setup — Defibrillator.
  • Correct potassium, magnesium and calcium, and stop the culprit drug (digitalis, verapamil, diltiazem, beta-blockers including glaucoma eye drops, clonidine, amiodarone, ivabradine) — hyperkalaemia with tall tented T waves and broad QRS is treated on the ECG before the result returns.Not available at your setup — Serum electrolytes. No electrolytes available: treat hyperkalaemia on the ECG picture alone.
  • Atropine 0.5–0.6 mg IV bolus, repeated every 3–5 minutes to a maximum cumulative 3 mg. Child: 20 microgram/kg IV/IO (minimum single dose 100 microgram, maximum 600 microgram), repeated once, for clearly vagal bradycardia or organophosphate poisoning only.Doctor / Nurse
  • Never give a single atropine dose below 0.5 mg — sub-therapeutic doses cause paradoxical vagotonic slowing.
  • If atropine fails — infusion: isoprenaline 2 mg in 500 mL 5% dextrose at 10–60 mL/hour (about 0.7–4 microgram/min) or 2–20 microgram/min titrated; or dopamine 5–20 microgram/kg/min IV; or adrenaline 2–10 microgram/min where bradycardic *and* hypotensive. In children adrenaline is first line: 10 microgram/kg IV/IO (0.1 mL/kg of 1:10 000) every 3–5 minutes or 0.05–0.3 microgram/kg/min.Doctor / NurseNot available at your setup — Infusion pump.
  • When drugs fail, pace — transcutaneous pacing is the most expeditious technique: demand mode, rate 60–80/min in an adult, output up from zero in 5–10 mA steps until capture plus a safety margin. Confirm capture twice — electrical (spike followed by broad QRS and T wave) and mechanical (femoral or brachial pulse at the paced rate, never the carotid).Doctor / NurseNot available at your setup — Defibrillator. No pacer: percussion pacing — firm rhythmical fist blows over the lower left sternal edge from about 10 cm at 50–70/min — bridges seconds while help is arranged.
  • If drugs and pacing all fail, ask what was swallowed: glucagon 5–10 mg IV then 1–5 mg/hour (beta-blocker poisoning); 10% calcium gluconate 10–20 mL IV over 5–10 minutes (calcium-channel blocker); atropine 1.2–2.4 mg IV plus digoxin-Fab (digoxin); atropine 1.2–2.4 mg IV in escalating doses until secretions dry (organophosphate).Doctor / Nurse
  • Child: airway, oxygen and ventilation first and usually suffice; if the rate stays below 60/min with poor perfusion despite effective oxygenation and ventilation, start chest compressions; use intraosseous access at the same doses if cannulation fails.
  • Never give IV verapamil to a patient on a beta-blocker, and never lower the blood pressure in the Cushing response (bradycardia + hypertension + falling conscious level = raised intracranial pressure — CT head is mandatory).

Read the escape complex

Narrow (QRS < 0.12 s)Broad (QRS > 0.12 s)
Level of blockAt/above AV nodeBelow His bundle
Escape rate50–60/min15–40/min
ReliabilityRelatively reliableUnreliable — this rhythm stops
AtropineOften effectiveUsually ineffective

Refer / escalate

Call for help and transfer urgently: any bradycardia with an adverse feature (systolic BP < 90 mmHg, syncope, ischaemia, heart failure, rate < 40/min, pause > 3 s), Mobitz II or third-degree block or a broad escape even if asymptomatic, bradycardia with anterior myocardial infarction, or anyone needing pacing, digoxin-Fab or monitoring you cannot provide.

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