Level 1 of 6Core
Shock: recognition and resuscitation
The core to-do list — diagnose and manage, at a glance
Diagnose— recognise it
- Shock is a diagnosis of perfusion, not of blood pressure: hypotension is conventionally SBP below 90 mmHg or MAP below 60–65 mmHg, but a chronic hypertensive may be profoundly shocked at 130/80 mmHg — judge against the patient's own baseline and follow the trend.
- Read the three windows: brain — new confusion, agitation or a falling GCS; kidney — urine output below 0.5 mL/kg/hr (child below 1, infant below 2); skin — cold, pale, clammy peripheries with capillary refill over 3 seconds in an adult or 2 in a child, mottling ascending from the knee.
- Three bedside questions sort almost every case: are the peripheries warm or cold; are the neck veins raised or flat; is the chest wet or dry? Cold with raised veins and a clear chest is obstructive shock — the group with the shortest time to collapse.
- Record the bedside numbers: capillary glucose; lactate (above 2 mmol/L defines septic and cardiogenic shock — repeat at 2 and 6 hours); shock index above 0.9 abnormal; qSOFA two or more of SBP below 100, RR above 22, GCS below 15.Not available at your setup — Arterial blood gas.
- Seek the immediately lethal, specifically treatable causes on the first pass: tension pneumothorax (absent breath sounds, hyper-resonance, tracheal deviation); tamponade (raised JVP, muffled sounds, pulsus paradoxus); anaphylaxis (urticaria, wheeze, angio-oedema after exposure); right ventricular infarction (inferior ST elevation, raised JVP, clear lungs); massive pulmonary embolism; meningococcal sepsis (non-blanching rash); adrenal crisis (fluid- and vasopressor-unresponsive hypotension with hyponatraemia and hypoglycaemia).
- Children compensate far longer and then crash: hypotension is pre-terminal (SBP below 70 in infants, below 70 + 2 × age at 1–10 years, below 90 over 10) — hunt instead for central capillary refill over 2 seconds, tachycardia for age, cool mottled peripheries, weak peripheral with strong central pulses, and irritability progressing to lethargy; bradycardia in a shocked child is a pre-arrest rhythm.
Manage now— do this, in order
- Treat and diagnose at the same time: oxygen titrated to SpO₂ 92–95%; two peripheral cannulae of 16 or 18 gauge (intraosseous if peripheral access fails in a peri-arrest patient); catheterise for hourly urine, attach monitoring, record a 12-lead ECG and capillary glucose.Doctor / Nurse
- Fluid by type of shock: septic/distributive — 30 mL/kg in the first hour as 500 mL aliquots with reassessment after each (children 10–20 mL/kg over 10–20 minutes); haemorrhagic — blood, not crystalloid (crystalloid is a bridge only); cardiogenic — 250 mL challenges only, auscultating the chest after each; massive PE — 500 mL of 0.9% sodium chloride then stop. Prefer balanced crystalloid; never hydroxyethyl starch.Doctor / Nurse
- Reassess the same five things after every bolus: pulse and blood pressure; capillary refill and peripheral temperature; respiratory rate and oxygen requirement; the lung bases for new crackles; and mental state. Stop and reconsider on new basal crackles, rising oxygen requirement, visibly raised JVP, or no improvement after 30 mL/kg — in children, if shock persists after 40 mL/kg consider elective intubation rather than further boluses.
- Noradrenaline is the first-line vasopressor: start 4–8 microgram/min IV (about 0.05–0.1 microgram/kg/min), titrate every 5 minutes to MAP of at least 65 mmHg; refractory shock may need 10–30 microgram/min; children 0.05–0.1 microgram/kg/min. In severe hypotension do not wait until 30 mL/kg has been given.Doctor / NurseNot available at your setup — Infusion pump.
- Anaphylaxis: remove the trigger and give adrenaline 500 microgram (0.5 mL of 1:1000) IM into the anterolateral thigh, repeated every 5 minutes if no improvement — children 10 microgram/kg IM (150 microgram under 6 years, 300 at 6–12, 500 over 12) — with generous IV crystalloid; antihistamine and corticosteroid are adjuncts, never substitutes.
- Antibiotics within one hour of recognising septic shock, after cultures where these can be taken promptly — inability to obtain cultures must not delay treatment. Paediatric first-hour cover: ceftriaxone 80 mg/kg IV once daily or cefotaxime 50 mg/kg IV 6-hourly (neonates under 28 days: cefotaxime plus amoxicillin or ampicillin). In severe invasive group A streptococcal infection add clindamycin 900 mg IV 8-hourly to benzylpenicillin 2.4 g IV 4-hourly. Drain the source.Doctor / NurseNot available at your setup — Blood culture.
- Suspected adrenal crisis: hydrocortisone 100 mg IV immediately with fluid and glucose (children 2 mg/kg IV, maximum 100 mg) — do not wait for a cortisol result; in septic shock with an ongoing vasopressor requirement give hydrocortisone 50 mg IV 6-hourly.Doctor / Nurse
- Mechanical emergencies: tension pneumothorax — immediate needle decompression before any imaging, then an intercostal drain; tamponade — fluid to maintain filling, then pericardiocentesis or surgical drainage; bradycardia with hypotension — atropine 500 microgram IV every 3–5 minutes to a maximum of 3 mg (children 20 microgram/kg, minimum 100, maximum 600 microgram).Doctor / NurseNot available at your setup — Chest drain / tube thoracostomy.
- Never give nitrates or diuretics in right ventricular infarction — give fluid instead, and avoid nitrates when the systolic pressure is below 90 mmHg.
Fluid: the dose depends on the type
| Setting | Adult bolus | Paediatric bolus |
|---|---|---|
| Septic / distributive | 30 mL/kg first hour, 500 mL aliquots | 10–20 mL/kg over 10–20 min |
| Non-haemorrhagic hypovolaemia | 500 mL boluses | 10–20 mL/kg over 10–20 min |
| Haemorrhagic | Blood, not crystalloid | Packed red cells 10 mL/kg, warmed |
| Cardiogenic | 250 mL challenges only | Small aliquots, specialist |
| Massive PE | 500 mL 0.9% saline, then stop | Small aliquots, specialist |
Refer / escalate
Call for help and arrange transfer at once for any shock persisting after adequate volume, any obstructive cause needing a procedure (tension pneumothorax, tamponade, massive PE), infarct-related cardiogenic shock needing PCI or thrombolysis, uncontrolled haemorrhage needing surgery or endoscopy, or a shocked child — and target intensive care admission within 6 hours of initial stabilisation.
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